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Glymphatic system as a gateway to connect neurodegeneration from periphery to CNS

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Byndloss MX, Olsan EE, Rivera-Chvez F et al (2017) Microbiota-activated PPAR- signaling inhibits dysbiotic Enterobacteriaceae expansion

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Nonetheless, the observation that adolescent alcohol exposure decreases BDNF-AS methylation in the amygdala reveals new mechanisms of RNA regulation that add another layer of complexity of epigenetic regulation of BDNF expression in AUD