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In diet-induced obesity (DIO) models, NNMT loss-of-function and selective small-molecule inhibitors reduce white adipose mass and improve metabolic parameters without overt toxicity, positioning NNMT as a tractable target for metabolic-disease research [24]

Great Potential in the Treatment of Metabolic Diseases With the high prevalence of metabolic diseases worldwide, 5-amino-1-methylquinolinium has shown outstanding performance in animal models of obesity, glucose metabolism disorders, fatty liver disease and other conditions

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No human safety data exists

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