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doi: 10.1093/bioinformatics/bth349 23 RamrezFDndarFDiehlSGrningBAMankeT

The interplay between these RCD pathways and the immune system is critical, as their activation can convert immunologically cold tumors into hot tumors, enhancing immune cell infiltration and responsiveness to immune checkpoint blockade (ICB) therapies ( The immunogenic nature of ferroptosis, pyroptosis, and necroptosis is particularly relevant in the context of melanoma immunotherapy

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