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Combination Approaches These approaches are not mutually exclusive

A recent study indicated that GSK-3 activity is upregulated under OS (196)

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Briefly, these studies revealed that DSePA treatment (at concentrations which are non-toxic for normal cells) inhibited the growth of lung cancer cells by causing reductive stress (marked by the increase in the levels of GSH and GPx) followed by mitochondrial and endoplasmic reticulum-dependent apoptosis [92]

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