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This ensures every vial meets global standards for sterility, purity, and potency

If intranasal bioavailability is 10% relative to subcutaneous, a 10-fold higher nasal dose would be needed to match exposure, but ceiling effects, tolerability, and mucosal volume limits complicate this further

[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Jones C.B., Eltit J.M., Dukat M