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While iron is essential for normal cellular function, its excess catalyzes the Fenton reaction, generating reactive oxygen species (ROS) that damage lipids, proteins, and DNA

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10.17221/107/2010-PSE Plant Soil Environ

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Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity

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We previously established that HIF-2 loss in UPS tumours leads to enhanced mechanistic target of rapamycin complex 1 (mTORC1) signalling 38 , a key pathway in nutrient sensing, cellular growth, and ribosomal biogenesis

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Additional staining was performed using an Abcam immunohistochemistry kit for MCP-1 as a measure of general neuroinflammation

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NOX family NADPH oxidases: not just in mammals

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