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Lipid-Based Nanocarriers Lipid-based systems are frequently employed for ocular delivery due to their compatibility with the lipid-rich corneal epithelium, which enhances permeation compared to aqueous solutions

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Loss of Ozz or Alix in vivo disrupts the steady-state levels of Slc25A4, impairing mitochondrial metabolism and triggering a switch in muscle fiber composition from oxidative, mitochondria-rich slow to glycolytic fast fibers

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9, 11 The turnover of the myocardial triglyceride pool is high and represents an important source of fatty acyl-CoA that subsequently is metabolized by the mitochondria