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DATROWAY (sBLA), June 2 AstraZeneca FDA decision on DATROWAY for the treatment of adult patients with unresectable or metastatic triple negative breast cancer who are not candidates for immunotherapy

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The reasons why patients benefit from lymphodepletion prior to ACT are not fully understood, and co-depletion of regulatory cells [26], an increase of serum cytokines [27,28], and tolerization towards xenogeneic sequences [29] have been discussed