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ARNTL is overexpressed in db/db mice, while the knockdown of ARNTL reduces oxidative stress in plasma and improves the classical morphological changes associated with renal ferroptosis [81]
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Furthermore, for the isoprenoid tail to be attached, 4-HB must be transported into the mitochondrial matrix, where the condensation with the tail occurs
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doi: 10.1007/s00702-017-1797-5 120
