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Surgical and Radiologic Anatomy, 37(9):1013-20 Dufresne F, Simmons B, Vlachostergios P J, Fleischner Z, Joudeh R, Blakeway J, Julliard K (2015)

Most frequently mentioned adverse effects of increased lysine intake, primarily in the form of lysine hydrochloride, include symptoms of impaired gastrointestinal function, such as nausea, abdominal pain, and diarrhea

Compared to beef, bison is naturally lower in calories, total fat, and saturated fat while providing comparable or higher levels of protein, iron, zinc, and vitamin B12

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Rebouche, C.J

Further studies are required to clarify the specific mechanisms by which TMAO impacts B cell biology