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Achieving a balance between mucus penetration and cell uptake is still challenging because the neutral, hydrophilic surfaces that benefit mucus penetration can limit interactions with epithelial cells unless they incorporate features such as positive charges or targeting molecules

In one example, Chen et al

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Antibodies were directed against proteins implicated in key pathways such as apoptosis, cell cycle regulation, senescence, DNA repair/damage and oxidative stress

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Riboflavin is best known for its use in migraine prophylaxis where doses are often 400mg daily orally
