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Reflectance confocal microscopy and dermoscopy are valuable adjuncts for better diagnosis when paired with recently described features

36 , e22186 (2022)

Consistently, recent evidence demonstrated that, beyond motoneuron hyperexcitability, spinal circuits in SMA undergo a maladaptive increase in inhibitory synaptic drive, resulting in a disrupted excitation/inhibition balance that further compromises motor output [35]

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