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However, the FDA to pulled approval of Avastin for breast cancer treatment in November 2011after a review of four clinical studies (FDA 2012)

Proc Natl Acad Sci U S A 89:1187611880 Goes N, Urmson J, Vincent D, Ramassar V, Halloran PF (1996) Effect of recombinant human insulin-like growth factor-1 on the inflammatory response to acute renal injury

[DOI] [PMC free article] [PubMed] [Google Scholar] 99.De Souza CT et al

When evaluating adipose tissue in WT and 3-KO mice, researchers found that neither treatment significantly affected white adipose tissue mass in either genotype