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[DOI] [PMC free article] [PubMed] [Google Scholar] Luchini A.C., et al

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2025;12:e2408618

12 In this study, a mixture of Lactobacillus acidophilus and Lactobacillus bulgaricus administered orally to 300 patients with acne (treatment for eight days, followed by two weeks of washout followed by two more weeks of treatment) demonstrated varying levels of improvement in 80 percent of patients

Tap water introduces bacteria, minerals, and chemicals that degrade the peptide and create infection risk

For instance, long-term studies with the IL-23-targeting therapy tildrakizumab showed an excellent response over time and long-term maintenance of response