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Surgery may not be a choice if you have other health problems, because of the higher risks

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization

However, this path has notable challenges, including balancing efficacy with genomic safety risks and navigating tissue-specific repair dependencies

doi: 10.1097/AOG.0b013e318255004e

Payne CT, Zhang F, Lloyd AM

In parallel, high-priority synthetic lethal targets were also selected as part of the MetDP framework