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ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control

Wasting syndrome

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10.1073/pnas.93.19.10417 15

The angiopoietin/Tie-2 system regulates pericyte survival and recruitment in diabetic retinopathy

Abstract Background: For many drugs, steady-state concentration-time profiles are often not optimally characterised by the intrinsic terminal elimination half-life for various reasons, including multiexponential disposition with minimal contribution of the terminal phase to steady-state exposure or use of controlled-release formulations with extended zero- or mixed zero-/first-order absorption