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Understanding these energy metabolism effects is relevant to research on obesity and metabolic health
doi:10.1016/0049-3848(84)90189-0 Wang JP, Hsu MF, Hsu TP, Teng CM

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doi: 10.1038/nrd781

In general, its recommended to apply tretinoin in the evening before bed rather than during the daytime
11 , 819, doi: 10.15252/msb.20156123 (2015)
