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Indeed, animal studies have demonstrated that the ALCAR/ALA combination improves mitochondrial functioning by increasing metabolism and lowering oxidative stress more than either compound alone 2830 and combined mitochondrial-enhancing compounds have shown more promise than single agents for the treatment of mitochondrial disorders

doi: 10.3390/metabo15040220

A., Org E., Wang Z., Levison B

Goodwin S, McPherson JD, McCombie WR : Coming of age: ten years of next-generation sequencing technologies

(currently Cincinnati Childrens Hospital, Cincinnati, OH)

L'effet demeure faible et non significatif pour des doses respectivement 2, 4 et 8 fois plus leves.The effect remains weak and not significant for doses 2, 4 and 8 times higher respectively