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CS induces S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), leading to its inactivation, reduced ECAR, decreased ATP production, and impaired pyruvate generation ( The core driver of aberrant glycolysis in COPD patients lies in the dysregulation of molecular regulatory networks

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Cancer risk Elevated COX-2 enzyme levels are present in actinic keratosis (AK) and SCC [186]

Ras leads to the activation of different mitogen-activated protein kinase (MAPK) cascades, including extracellular-signal-regulated kinase (ERK), p38 MAPK , and c-Jun N-terminal protein kinase (JNK) (Graziani et al., 1993)

Vitamin B6, B9, and B12 Intakes and Cognitive Performance in Elders: National Health and Nutrition Examination Survey, 20112014