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However, KD failed to improve motor performance in the rotarod test or prevent brain atrophy, indicating that while KD may modulate metabolic aspects, it does not appear to fully prevent neurodegeneration in transgenic HD mice [98]

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Genistein is capable of inducing apoptosis of Bcl-2-silenced malignant neuroblastoma cells by both ligand- (Fas ligand/TNF-related apoptosis-inducing ligand) death receptor- (Fas/TNF receptor) mediated extrinsic and mitochondria-dependent intrinsic pathways [155]

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