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Skin saturation limits how much peptide penetrates regardless of concentration

It is commonly used for managing back pain , sciatica , neuralgia , joint pain , and other musculoskeletal conditions where nerve health and inflammation are concerns

Raj GM, Raveendran R (2019) Introduction to basics of pharmacology and toxicology: volume 1: general and molecular pharmacology: Principles of drug action

Kannt et al

Caution is recommended in individuals with seizure disorders, as increased frequency or severity of seizures has been reported during therapy

It is used in laboratory settings for the reconstitution of research compounds