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Given that apo A and apo B are principal components of HDL-C and LDL-C, respectively, these findings align with theoretical expectations (150)

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Next, cDNA was synthesized by reverse transcription using the QuantiTect Reverse Transcription Kit from Qiagen according to the manufacturers instructions, and qRT-PCR was finally performed using a QuantiTect SYBR Green PCR Kit and QuantiTect Primer Assays (Qiagen) on a LightCycler 480 instrument (Roche)

doi: 10.1080/10611860290031912

This suggests the need for structure-activity relationship studies that need to be conducted on these metabolites