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Choline deficiency causes hepatic steatosis (fatty liver disease) and leads to loss of muscle membrane integrity

AOD-9604 is a synthetic 16-amino acid peptide fragment derived from the C-terminal region of human growth hormone (amino acids 176-191)

For a medication that users store in home refrigerators for weeks after reconstitution, stability matters

The doses used in trials were around 500ug/kg, which means a 100kg person was receiving 50mg of the peptide daily. $50 million in research and development down the drain for a promising product that was no longer a viable pharmaceutical product