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In line with previous work 6,23 , wildtype hOCTN2 has an apparent K M for carnitine in the low micromolar range of 12.0 3.0 M (at 100 mM external [Na + ])

Musser RE, Dritz SS, Davis DL, Tokach MD, Nelssen JL, Goodband RD, Owen KQ

These cells were exposed for 24 h to L-Carnitine, acetyl-L-Carnitine, or both at concentrations ranging from 50200 mM

Mayatepek E, Nezu J, Tamai I, Oku A, Katsura M, Shimane M, Tsuji A: Two novel missense mutations of the OCTN2 gene (W283R and V446F) in a patient with primary systemic carnitine deficiency