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doi:10.1074/jbc.M805586200, PMID: 18990698 Borutaite V, Brown GC (2007) Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state

In addition, the presence of comorbid conditions, such as chronic pain or autoimmune disorders, can exacerbate the inflammatory response and further complicate the clinical picture of depression [293,294]

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It fulfills this role by protecting mitochondria organelles that produce a large portion of chemical energy required to power the cells biochemical reactions from oxidative damage (aka oxidative stress)

DAT and NET both transport AMPH, although NET has an approximate 1.5-fold higher apparent affinity (Table 1)