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A fasting-mimicking diet had synergistic effects with vitamin C in KRAS -mutated CRC cells [75]
EGFR targeting therapies provide no benefit in KRAS/BRAF -mutated CRC cells
This impairs cellular functions and further exacerbates mitochondrial dysfunction [58]
By inhibiting the phosphatase action of PTP1B on the insulin receptor (IR) and insulin receptor substrates (IRS) proteins, insulin sensitivity is increased, and consequently better glycemic control is generated
doi: 10.2174/1871530319666190329114621 79 ZhaoZLiJSongNGaoHJinZChenYet al
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