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In particular, the Nlrp3 inflammasome is a cytosolic multiprotein complex expressed in immune/inflammatory cells as well as cardiovascular system cells, including endothelial cells, myofibroblasts/fibroblasts, and cardiomyocytes, which, through the processing and release of interleukin (IL)-1 and IL-18 and the induction of cell death processes (pyroptosis, apoptosis, and necroptosis), plays a key role in the maintenance of host homeostasis and in sustaining the pathophysiological events underlying CVDs (48)

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Endocrinology 153 , 51435149 (2012)

Evidence for the involvement of carnitine-dependent long-chain acyltransferases in neuronal triglyceride and phospholipid fatty acid turnover

Ursolic Acid, a triterpenoid from the evergreen climbing shrub Arctostaphylos uva-ursi (L.) Spreng

DRMs were subsequently classified on the basis of the HMDB metabolite database, including lipids and lipid-like molecules (31.62%), organic acids and derivatives (24.26%), organoheterocyclic compounds (13.24%), and organic oxygen compounds (7.35%) (Fig