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Lateral NAc Shell D1 and D2 Neuronal Ensembles Concurrently Predict Licking Behavior and Categorize Sucrose Concentrations in a Context-dependent Manner

As a byproduct, harmful free radicals occur, causing oxidative damage

The mitochondrial deacetylase SIRT3 promotes BNIP3-mediated mitophagy against hepatocyte apoptosis via the extracellular signaling regulated kinase-cAMP-responsive component binding protein signaling pathway [194, 195]

However, whether dysbiosis is a driver of intestinal barrier dysfunction and liver injury, or instead represents a secondary consequence of hepatic pathology, remains unresolved