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Afamelanotide is a treatment for a rare condition called erythropoietic protoporphyria which causes severe pain on sun exposure

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A phase 1 clinical trial demonstrated that a dose of 10 mg/kg/day of CBDV is safe and well tolerated in a pediatric Rett syndrome cohort and suggests improved seizure control (131)

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On dermoscopy, the colour is uniform and equal in diameter at the proximal and distal ends of the band, which may arise within a pale brown background

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