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Subsequently, DP breaks cysteinyl glycine into cysteine and glycine, which are reabsorbed into the cell to engage in a novel GSH synthesis pathway (summarized in Fig

Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes

In particular, when adding Rieske-type Fdx PsFdx1 into the catalytic reaction system, the AD conversion rates of KshA + PRF + PsFdx1 and KshA + PRF + DmFdx2 were 80.6% and 85.2% (Additional file 1: Fig

ROS promotes receptor interacting serine/threonine kinase 3 (RIP3) phosphorylation, which subsequently triggers downstream mixed lineage kinase domain-like pseudokinase (MLKL) phosphorylation and activates MLKL translocation to the plasma membrane, increasing membrane permeability and inducing necrotic death in HCC tumor cells [125]

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Gebert LFR, MacRae IJ