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Standard dosage: 510 mg per day
Using our 337-gene panel, we compared PFC and NAc expression profiles across exposures and sex (Fig
doi: 10.1016/j.nbd.2007.11.004
Even after drug withdrawal, treatment-induced chromatin landscape alterations (e.g., reduced H3K27me3 at key gene promoters) may persist, enabling cells to more rapidly initiate resistance mechanisms upon re-exposure to the same treatment [162, 163]
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