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Mild symptoms may improve with conservative care, especially if constipation or straining is the main trigger

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Two studies from the early 1980s suggest that dietary concentrations of 2.03.0 ppm would be required to meet tissue needs and to increase reproductive performance (Easter et al., 1983

It can be observed that although the STS administration protocols vary across studies, they consistently demonstrate therapeutic benefits and a relatively favourable safety profile [5153]

Another possibility is that initial plasma selenium levels were higher in the SELECT population compared with previous studies

PMC 523398