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Together, these findings identify EAR-20 as a novel subunit-dependent positive allosteric modulator with the potential to inspire the development of small molecules targeting the same binding site, offering proof of concept for therapeutic strategies to treat neurological and neurodevelopmental disorders

krlec K, Ruman R, Jarc E, Sikiri P, vajger U, Petan T, Perii Nanut M, trukelj B, Berlec A (2018) Engineering recombinant Lactococcus lactis as a delivery vehicle for BPC-157 peptide with antioxidant activities

Finally, we observe multiple contexts where chronic exposure to various drugs that target redox pathways have effects that are very different to their effects after acute administration

10.1016/j.cell.2017.09.021 126 SucherE.SucherR.GradistanacT.BrandacherG.SchneebergerS.BergT

Nutrients 14, (2022)

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