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Preclinical animal studies further validate its neuroprotective potential: phillyrin A improves learning and memory in senescence-accelerated mice, activates the Nrf2 signaling pathway in APP/PS1 mice, upregulates antioxidant proteins (NQO1, GPX4), and normalizes cerebral iron content through modulation of TFRC, DMT1, FTH, and FTL gene expression (234)
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(82) found in a study of acetyl levocarnitine (ALC), metformin, and pioglitazone in the treatment of PCOS that the combination of ALC in the treatment of PCOS could more effectively reduce the fasting insulin level and significantly improve the levels of serum total testosterone, FSH and LH
doi: 10.1007/s00394-013-0561-3
This protocol guide is provided solely for educational and research purposes
10.1016/j.molmet.2021.101203
