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This is achieved in an oxidation step mediated by PDI oxidoreductases (protein disulfide isomerases) [for details, see Lenzen (2017)].The ER acts as a H 2 O 2 store, keeping a greater amount of the generated H 2 O 2 in the ER due to a limited efflux of H 2 O 2 into the cytosolic space
Curi, et al
The study found that dyspareunia, referred pain, menstruation-exacerbated bowel symptoms, and a family history of endometriosis were significantly associated with the co-occurrence of both conditions
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Thus, in epithelial lung cells, the Fas receptor is glutathionylated on Cys294 during degradation of Grx1 involving caspase-8 and/or caspase-3, this resulting in the acceleration of apoptosis [173]
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