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It should be kept in mind that orexin may regulate sleep/wakefulness states, rather than feeding behavior (Hungs and Mignot, 2001

[Google Scholar] 26.Nordberg A, Wahlstrom G, Arnelo U, Larsson C

Sleep and Withdrawal For regular e-cigarette users, going without nicotine overnight may trigger withdrawal symptomsrestlessness, irritability, and vivid dreamswhich can also disrupt sleep

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