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The implications of relying on pack-year history alone while not considering duration of smoking are substantial for lung cancer, in particular regarding population screening with low-dose CT

Internal tobacco industry documents made public through US litigation settlements show that tobacco companies have promoted separate seating for smokers and ineffective ventilation technologies [ 73 ]

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Men with 20 pack-years had an aHR of 1.29 (95% CI 1.181.42), while women with 10 pack-years had an aHR of 1.75 (95% CI 1.122.73) for MASLD with significant fibrosis [60]

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Then action the first take and then a second and so on up to 10