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30 Nicotine is metabolized primarily to cotinine, which is further metabolized to trans-3-hydroxycotinine (3HC), catalyzed by the liver cytochrome P450 2A6 enzyme

"You've got tobacco from Thailand, you've got tobacco from Macedonia, you've got tobacco from Turkey, you've got tobacco from Kentucky and Tennessee, you've got tobacco from Virginia, and you've got tobacco from North Carolina

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Rated 5 out of 5 Tristan (verified owner) Ideal for those who appreciate a more natural, earthy profile, with an undeniable difference from non-organic blends