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Additional petition sponsors include African Tobacco Control Alliance, Action on Smoking & Health, Coalicin Amrica Saludable, Southeast Asia Tobacco Control Alliance, and European Network for Smoking and Tobacco Prevention

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In adults that were isolated as adolescents, pyramidal neurons of the prefrontal cortex are insensitive to modulation of synaptic response amplitude by dopamine and do not develop the late onset inhibitory regulation by D 2 receptors that is seen in normal adults (Tseng & O'Donnell, 2007)

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