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British American Tobacco operates in 180+ markets so these measures materially affect margins

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Prior to selling a new tobacco product, companies must submit and receive approval based on a premarket tobacco product application (PMTA), which provides information about the product, such as the ingredients, potential health risks and benefits, and methods used in manufacturing and processing 3

Previous research 25 using functional magnetic resonance imaging has shown that while activation of the reward circuit (ventral striatum) appears in response to tobacco-related rewards in nicotine dependence, responses to rewards other than tobacco (e.g