Smoking One Cigarette a Day Health Risks
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Description
The activation and/or upregulation of many xenobiotic metabolism enzymes is driven by exposure to chemicals that can serve as substrates
doi: 10.3109/00365517709091490
However, it should be noted that MAPKs may be inhibited by cigarette smoke in later stages of diseases and lead to a more M2-like phenotype
Metabolism 54 , 247254 (2005)
Am J Epidemiol 2002
This sense of familiarity makes it a perfect starting point for smokers
