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While youve probably heard stories or urban legends about someone who used a certain drug just one time and became addicted from that first-time use, developing a tolerance, becoming dependent, and experiencing physical and/or behavioral addiction to a substance occurs in a complex, progressive process

PLoS Med

Despite the temporary setback in medication availability, campaigns that promote quitting and encourage medication usage may be one of the most logical public health strategies we can deploy

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In the present study, we demonstrated that incubation with CSE or acrolein induces the formation of high molecular weight oligomers, acroleinlysine adducts, and aldehyde adducts in hSP-A (Figs 2 and 3)