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So, by silencing the circuit, we were able to demonstrate for certain that this was a very important neural encoder of the behavioral aspect of high-dose nicotine. The only drug designed to help with nicotine cessation, varenicline, could work by increasing aversion via the alpha-7 receptor and lessening desensitization of the alpha-4/beta-2 receptor, she said, but its precise mechanism of action is currently unknown

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Nicotine & Tobacco Research, 2004

Tobacco corporations regarded sponsorship of Formula 1 racing teams as a chance to sell their goods to lots of people than they had previously imagined

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