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In males, smoking can cause impotence by damaging blood vessels in the penis

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========== Over 35 million people use e-cigarettes globally, and China is the world's leading manufacturer of e-cigarettes

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The present study, as part of the Global Burden of Diseases, Risk Factors, and Injuries Study (GBD) 2020, re-estimated the continuous doseresponse relationships (the mean risk functions and associated uncertainty estimates) between current smoking and 36 health outcomes (Supplementary Table 1) by identifying input studies using a systematic review approach and employing a meta-analytic method 28