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The team must address the issues before moving forward

Among these harmful chemicals are ammonia, arsenic, formaldehyde, acetone, and numerous others, which are known to be detrimental to human health

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66,67 Therefore, miRNAs should not be seen as independent diagnostic markers, but rather as possible parts of multi-marker panels that may better reflect OA heterogeneity, including inflammatory phenotypes that may be more common in smoking-related disease