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Studies show that smoking leads to brain atrophy, especially in areas critical for memory, learning and decision-making, such as the hippocampus and frontal cortex. The toxic chemicals in cigarettes, such as nicotine and carbon monoxide, also restrict blood flow to the brain therefore reduce oxygen supply to brain cells, explains the neurologist

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Epigenet 6 , (2020)

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However, spontaneous germ cell necrosis takes place very sporadically in the testes of wild type or Tp53-/- mutant mice at 6-8 weeks of age ( Table 1 Several phenotypes associated with spermatogenesis and function caused by Tp53 genomic knockout or overexpression