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qNMR spectroscopic analysis of cold trap components 1 H NMR spectra were acquired using a 30 observation pulse, a relaxation delay of 60.0 s, and 64 scans, using a Bruker Avance II + 400 MHz or Avance III 600 MHz spectrometer

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Many characteristics of these trials, such as short durations, confined settings and choice of comparators and participants, are not representative of real-world use and fail to adequately investigate whether HTPs reduce harm and are beneficial to public health