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[66] combined the microgram weight of the compound in the smoke of one cigarette with the known genotoxic effect per microgram to identify the most carcinogenic compounds in cigarette smoke

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Taken together, the homeostasis of MDM2p53 axis can promote hepatocyte proliferation, xenobiotic detoxification, and OXPHOS-mediated energy metabolism

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Intensified Anti-Tobacco Public Campaigns WHO Framework Convention on Tobacco Control signatories have extended mass-media campaigns beyond combustibles to encompass all tobacco and nicotine products, deploying graphic health warnings and testimonial advertising that emphasize oral cancer, gum disease, and cardiovascular risks associated with smokeless use

Consistently, it has been found that maternal smoking during pregnancy in mice can amplify oxidative stress and production of inflammatory cytokines in lungs of the offspring (Sukjamnong et al., 2017)