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Any way you look at it, this process will take years to work itself out, said Will Woodlee, a partner with the law firm Kleinfeld, Kaplan & Becker LLC, which has represented a wide range of tobacco and e-cigarette companies in their dealings with the FDA

Much of this has come from local government but the NHS has also made significant contributions

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Long-term animal studies for assessment of toxicity and carcinogenesis are not ideal models because of the requirement for long-term intensive smoke exposure, the length of time required to induce visible tumors, and the lack of an established robust animal model for cigarette smoke-mediated carcinogenesis