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[2] Cigarette smoking is responsible for 50% of all avoidable deaths in smokers, with half of these due to atherosclerotic cardiovascular diseases such as heart attack and stroke

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The Food and Drug Administration cant currently regulate electronic cigarettes because they dont technically contain tobacco -- even though the nicotine in them is derived from tobacco -- something that has angered e-cigarette opponents

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In some cases, associations were observed but did not reach statistical significance, and only a few studies included appropriate control groups, thus also leading to differences in quality between eligible studies

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